Giantin Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC-P, IHC-F, IF, ICC, E |
---|---|
Primary Accession | Q14789 |
Reactivity | Rat, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 376 KDa |
Physical State | Liquid |
Immunogen | KLH conjugated synthetic peptide derived from human Giantin |
Epitope Specificity | 751-850/3259 |
Isotype | IgG |
Purity | affinity purified by Protein A |
Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
SUBCELLULAR LOCATION | Golgi apparatus membrane. |
SUBUNIT | Homodimer; disulfide-linked. Interacts with PLK3. |
Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
Background Descriptions | The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Feb 2010] |
Gene ID | 2804 |
---|---|
Other Names | Golgin subfamily B member 1, 372 kDa Golgi complex-associated protein, GCP372, Giantin, Macrogolgin, GOLGB1 |
Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100,IF=1:100-500,Flow-Cyt=1 µg/Test,ELISA=1:5000-10000 |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | GOLGB1 |
---|---|
Function | May participate in forming intercisternal cross-bridges of the Golgi complex. |
Cellular Location | Golgi apparatus membrane; Single-pass type I membrane protein |

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